Read BookThe Effects of Melatonin on Menstrual Characteristics Prolactin and Premenstrual Syndrome-Like Symptoms during a Simulated Eastward Deployment

[Download PDF.qBYS] The Effects of Melatonin on Menstrual Characteristics Prolactin and Premenstrual Syndrome-Like Symptoms during a Simulated Eastward Deployment

[Download PDF.qBYS] The Effects of Melatonin on Menstrual Characteristics Prolactin and Premenstrual Syndrome-Like Symptoms during a Simulated Eastward Deployment

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Published on: 1997
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This is a ARMY AEROMEDICAL RESEARCH LAB FORT RUCKER AL report procured by the Pentagon and made available for public release. It has been reproduced in the best form available to the Pentagon. It is not spiral-bound, but rather assembled with Velobinding in a soft, white linen cover. The Storming Media report number is A160433. The abstract provided by the Pentagon follows: Melatonin (N-acetyl-5-methoxytryptamine),a natural hormone which has been shown to resynchronize circadian rhythms and induce sleep in humans (Arendt et al., 1987; Dawson and Encel, 1993; Reiter, 1991; Wurtman, 1986), is currently being marketed widely as a dietary supplement to alleviate desynchronosis (desynchronization of physiological and behavioral rhythms) and assist in obtaining quality sleep. Desynchronosis often results from rapid shifts in work schedules from day to night, or from shifts in the light- dark cycle due to time zone crossing. Symptoms resulting from desynchronosis include fatigue, sleepiness, lethargy, insomnia, gastrointestinal tract disorders, and poor mental performance (for review see Comperatore and Krueger, 1990). Melatonin therapy has been demonstrated to be effective in preventing sleep loss and in maintaining alertness following travel across multiple time zones (Arendt and Broadway, 1987; Comperatore et al., 1996; Petrie et al., 1989). Thus, melatonin can be a potentially effective chronobiotic and ameliorate desynchronosis during travel.
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